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CAS No. 356-12-7 | Fluocinonide

Name: Fluocinonide CAS No. 356-12-7 MF:C26H32F2O7 MW:494.52 Purity:98% Package: 5g,25g,200g,500g,1kg Worldwide Delivery

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Biochemicals

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Product introduction

Introduction and application of CAS No. 356-12-7 | Fluocinonide

Synonyms:Cortalar;

Fluocinonide

(6α,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-Methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

Flucetonide;

Specification:

ITEMS	SPECIFICATION
CAS	356-12-7
MF	C26H32F2O7
MW	494.52
Melting point	309 °C
Boiling point	235°C
Density	1.2
Acidity coefficient	12.77±0.70
Color	white to tan
Solubility	Dimethyl sulfoxide: ≥19mg/mL
Form	Powder
Storage condition	2-8°C

Introduction:

Fluocinolone acetonide, also known as fluocinolone acetate, chemical name 6α, 9α-difluoro-11β, 21-dihydroxy-16α, 17α-[(1-methylethylene)dioxy]pregnantrol-1,4- Disil-3,20-dike-21-acetate is a potent topical anti-inflammatory glucocorticoid drug commonly used in clinical practice. It is widely used in various dermatitis, eczema, psoriasis, lupus erythematosus, lichen planus and osseous diseases. Treatment of diseases such as arthritis.

Function and use:

This product is a fluoride-containing glucocorticoid. Topical application can constrict dermal capillaries. Because it can inhibit DNA synthesis and affect cell metabolism, it can inhibit the proliferation or regeneration of epidermal cells. It can also inhibit the regeneration of fibroblasts and the production of pigment cells in connective tissue. It can also stabilize intracellular lysosomal membranes and prevent intracellular lysosomal enzymes from releasing histamine and causing tissue damage. It is easily absorbed from the skin when used externally. It has anti-inflammatory, antipruritic, anti-proliferative and immunosuppressive effects. It can be absorbed through the intact skin after external use. The degree of absorption is affected by many factors, such as the matrix of the preparation, the pathological condition of the skin, and whether the drug is packaged. After absorption, it binds to plasma proteins. Mainly metabolized in the liver and excreted by the kidneys. Used for contact dermatitis, allergic dermatitis, seborrheic dermatitis, neurodermatitis, solar dermatitis, eczema, psoriasis, lichen planus and skin itching.

Package and transportation :

Package: 5g,25g,200g,500g,1kg